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Comprehensive Guide to Advanced Psoriasis Treatment: Effective Strategies for Clear Skin


Skin Care

Psoriasis is a chronic skin condition that affects millions of people worldwide. Characterized by red, scaly patches that can be itchy and painful, psoriasis can significantly impact a person’s quality of life. “How do I treat psoriasis?” you may ask. Fortunately, numerous advanced psoriasis treatments are available that can help manage and reduce the symptoms of psoriasis. This comprehensive guide explores various advanced psoriasis treatments, from topical solutions to systemic medications and lifestyle changes, to help you achieve clearer, healthier skin.

Understanding Psoriasis

Psoriasis, an autoimmune condition, triggers the rapid overproduction of skin cells, leading to thick, scaly patches on the skin. Although the exact cause remains unclear, it likely stems from genetic, environmental, and immune system factors. Stress, infections, specific medications, and skin injuries commonly provoke psoriasis flare-ups.

Topical Psoriasis Treatments

Topical treatments are often the initial approach to treating psoriasis. These are one among the advanced psoriasis treatments and are applied directly to the affected skin and can help reduce inflammation, slow down skin cell production, and alleviate itching.


Corticosteroids are anti-inflammatory medications that come in various strengths, from mild to potent. They are commonly used to reduce redness and inflammation associated with psoriasis. Corticosteroid creams and ointments should be used as directed by a healthcare provider to avoid potential side effects like skin thinning.

Vitamin D Analogues

Vitamin D analogues, such as calcipotriene and calcitriol, help slow the growth of skin cells. These treatments are often used in combination with corticosteroids to enhance their effectiveness. Vitamin D analogues are generally well-tolerated and can be used long-term with minimal side effects.

Topical Retinoids

Topical retinoids, like tazarotene, are derived from vitamin A and help normalize skin cell production. They can be effective in reducing the scaling and thickness of psoriasis plaques. However, retinoids can cause skin irritation, so they should be used with caution and under the guidance of a healthcare provider.

Coal Tar

For decades, coal tar has been utilized in the treatment of psoriasis. It helps reduce scaling, itching, and inflammation. Coal tar products are available in various forms, including shampoos, creams, and ointments. While effective, coal tar can be messy and has a strong odor, which may be a drawback for some users.

Systemic Psoriasis Treatments

For moderate to severe psoriasis that does not respond to topical treatments, systemic medications may be necessary. These advanced psoriasis treatments work throughout the body to control psoriasis symptoms.


Methotrexate is a commonly used systemic medication that suppresses the immune system to reduce inflammation and slow down skin cell production. It is usually taken once a week and can be effective in managing severe psoriasis. Regular monitoring is required to avoid potential side effects, such as liver damage and reduced blood cell counts.


Cyclosporine is another immunosuppressant that can be highly effective for severe psoriasis. It works quickly to reduce symptoms but is typically used for short-term treatment due to the potential side effects, including high blood pressure and kidney damage.

Biologic Drugs

Biologic drugs are a newer class of systemic medications that target specific parts of the immune system involved in psoriasis. These drugs, like adalimumab, etanercept, and ustekinumab, are usually administered via injection or infusion. Biologics can be highly effective in reducing symptoms and improving quality of life, but they can also increase the risk of infections and other serious side effects.

Phototherapy for Psoriasis

Phototherapy, also known as light therapy, entails exposing the skin to controlled amounts of natural or artificial ultraviolet (UV) light. This treatment can slow down skin cell production and reduce inflammation.

UVB Phototherapy

UVB phototherapy uses a specific wavelength of ultraviolet light to treat psoriasis. It can be administered in a healthcare setting or at home using a phototherapy unit. Regular sessions are required, and treatment should be supervised by a healthcare provider to minimize the risk of skin damage.

PUVA Therapy

PUVA therapy blends psoralen, a drug, with UVA light. Psoralen makes the skin more sensitive to light, enhancing the effectiveness of the treatment. PUVA is typically used for more severe cases of psoriasis and requires careful monitoring due to the increased risk of skin cancer and other side effects.

Natural and Home Remedies for Psoriasis

In addition to medical treatments, several natural and home remedies can help manage psoriasis symptoms. These remedies may not be as potent as prescription medications but can be beneficial as part of a comprehensive psoriasis care plan.


Keeping the skin well-moisturized is crucial for managing psoriasis. Thick, emollient moisturizers can help reduce dryness, scaling, and itching. Look for products containing ingredients like glycerin, urea, and hyaluronic acid.

Aloe Vera

Aloe vera has soothing and anti-inflammatory properties that can help alleviate psoriasis symptoms. Applying aloe vera gel to the affected areas can reduce redness and scaling.

Oatmeal Baths

Oatmeal baths offer relief from itching and irritation. Add finely ground oatmeal to a warm bath and soak for 15-20 minutes. This remedy can help soothe inflamed skin and lock in moisture.

Dietary Changes

Certain dietary changes may help reduce psoriasis flare-ups. Eating a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can support overall health and reduce inflammation. Some people with psoriasis find that reducing or eliminating alcohol, dairy, and gluten can also help manage symptoms.

Lifestyle Changes for Psoriasis Management

In addition to advanced psoriasis treatments and home remedies, certain lifestyle changes can help manage psoriasis and improve quality of life.

Stress Management: Stress often triggers psoriasis flare-ups. Engaging in stress-reducing activities like yoga, meditation, and regular exercise can effectively manage stress levels and decrease flare-up frequency.

Regular Exercise: Regular physical activity can improve overall health and reduce inflammation. Aim for at least 30 minutes of moderate exercise most days of the week.

Healthy Sleep Habits: Getting adequate sleep is essential for overall health and can help manage psoriasis symptoms. Aim for 7-9 hours of quality sleep each night.

Avoid Smoking and Limit Alcohol: Smoking and excessive alcohol consumption can worsen psoriasis symptoms. Quitting smoking and limiting alcohol intake can improve skin health and overall well-being.

Consulting a Dermatologist

For persistent or severe psoriasis, consulting a dermatologist is crucial. Dermatologists often recommend a personalized approach when answering “How do I treat psoriasis?” considering factors like the type of psoriasis and its impact on daily life. A dermatologist can provide an accurate diagnosis, recommend appropriate advanced psoriasis treatments, and monitor your progress. Professional guidance ensures that you receive the most effective and safe treatment for your specific condition.


Managing psoriasis requires a comprehensive approach that includes advanced psoriasis treatments, natural remedies, lifestyle changes, and professional guidance. By understanding the various treatment options available and working closely with a healthcare provider, you can effectively manage psoriasis symptoms and achieve clearer, healthier skin.

Dr. Stefan Weiss is an internationally renowned, board-certified dermatologist with over two anda half decades of experience providing his patients with the best, most advanced options for psoriasis treatment. Dr. Weiss takes a holistic approach and embraces a less-is-more philosophy, creating customized skincare routines and treatment plans that cater to the unique concerns and aesthetic goals of his patients. He is consistently identified as one of the Top dermatologists for his dedication to his patients and his expertise in psoriasis.

If you are concerned with psoriasis and are interested in learning more about advanced psoriasis treatment options, Dr. Stefan Weiss is a nationally-recognized expert in Chapel Hill in psoriasis treatment and can create a customized psoriasis treatment plan for you. Contact the office today or call 919-710-8100 to book an appointment with Dr. Stefan Weiss.

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